Sir Anthony Hopkins's portrayal of Hannibal the Cannibal that really gets under your skin.

Look at Hannibal Lecter. He's so charming! So articulate! So dignified, even strapped down with a bite guard over his face. He's just so ... alluring that you really would be tempted to accept his invitation to dinner. Which would be bad. 'Cause he eats people. (And washes 'em down with fine wine.) Sure, Buffalo Bill's flashy, hide-tanning efforts form the bulk of the film's plot, but it's Sir Anthony Hopkins's portrayal of Hannibal the Cannibal that really gets under your skin. Yet, despite his bewitching persona, no amount of Chianti can ever change the fact that Hannibal Lecter is one of cinema's greatest villains of all time.