The Mid-Cape, (around the "bicep"), is the most central location for resting your head. The Wequassett Resort and Golf Club, in Chatham, offers arguably the Cape's finest accommodations. (There are several award-winning inns and resorts on Martha's Vineyard and Nantucket, the two islands considered part of Cape Cod. But on the mainland, family-friendly motels and weekly cottage rentals dominate the hotel scene). The Wequassett offers an old-fashioned New England atmosphere combined with oceanfront luxury.

Just down the road is the Queen Anne Inn, a slightly less pricey romantic getaway. Families and those who want a little more nightlife should consider the motels in Hyannis, Cape Cod's largest town. Although they lack some of the charm of the B&Bs and historic inns, affordable options like the Sea Coast Inn are in walking distance of some of the Cape's most lively bars and clubs. And if history is your thing, consider the Belfry Inn & Bistro. A little less central than some of your other options, the Belfry is housed in a cluster of refurbished Victorians, including a striking former church.

For more accommodations on Cape Cod, see GAYOT's hotel reviews.