Natural Calm is a great stress fighter through its combo of both magnesium and calcium. In that sense it works much like an adaptogen, calming tense muscles (magnesium) while exciting tired nerves (calcium). Stress can cause magnesium deficiency, and magnesium needs its partner calcium to help your cells, and thus your entire body, function properly. We found Natural Calm to be amazing after physical exertion, during PMS and heavy periods and when feeling anxious and irritable. The water-soluble magnesium in Natural Calm is ionic, thus readily available and immediately effective.