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Floor-to-ceiling frescoes painted by the owner of this charming Italian restaurant make a fine backdrop for the food.


Lunch Mon.-Fri., Dinner nightly

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Operations may be disrupted due to COVID-19. Be sure to contact the restaurant to find out its current status and offerings.

Cafe Sistina Restaurant Review

: Cafe Sistina patrons aren’t likely to overlook the dining room's colorful hues mirroring Michelangelo’s frescoes, all painted by owner Sergio Mitrotti himself. The menu is trisected according to The Classics, The Contemporary and The Cutting Edge. This is a restaurant to eat simply, often late at night at the bar. We recommend ordering dishes Mitrotti's grandmother would have made: bruschetta con vongole and linguine alla puttanesca, a spicy marvel full of black olives, capers and anchovies. With a glass of Valpolicella Amarone or Frascati, it's a place to sit back and enjoy the food and the artistic surroundings. A full bar and a reputable wine list round out the experience.

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Stay in a romantic mood with this Rosé Champagne.

Read GAYOT's review.